Chronic Hepatitis B Virus
Findings from Chinese Academy of Sciences broaden understanding of chronic hepatitis B virus
Published in Hepatitis Weekly, December 27th, 2010
2010 DEC 27 -- New research, 'CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice,' is the subject of a report. "Chronic hepatitis B virus (HBV) infection is characterized by sustained liver inflammation with an influx of lymphocytes, which contributes to the development of cirrhosis and hepatocellular carcinoma. The mechanisms underlying this immune-mediated hepatic pathogenesis remain ill defined," researchers in Beijing, People's Republic of China report.
"We report in this article that repetitive infusion of anti-CD137 agonist mAb in HBV-transgenic mice closely mimics this process by...
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Source: Hepatitis Weekly (2010-12-27)
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