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Hepatitis C Virus

Investigators at Showa University Zero in on Hepatitis C Virus

Published in Hepatitis Weekly, February 21st, 2011

2011 FEB 21 -- "Because polymorphisms of cyclooxygenase-2 (COX-2) and osteopontin (OPN) promoter regions and a promoter/enhancer region of forkhead box protein 3 (FOXP3) gene are known to affect immune responses, we examined whether these polymorphisms can influence susceptibility to hepatitis C virus (HCV) infection and progression of liver disease. Peripheral blood samples were obtained from 104 Japanese patients with chronic HCV infection and 74 healthy Japanese donors," investigators in Tokyo, Japan report.

"Polymerase chain reaction single-stranded conformational polymorphism analysis of genomic DNA was performed to determine the polymorphisms. The...

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