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Hepatitis C Virus

Reports Summarize Hepatitis C Virus Research from Copenhagen University Hospital

Published in Hepatitis Weekly, April 4th, 2011

2011 APR 4 -- New research, 'Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations,' is the subject of a report. According to a study from Hvidovre, Denmark, "Hepatitis C virus (HCV) is an important cause of chronic liver disease, and interferon-based therapy cures only 40 to 80% of patients, depending on HCV genotype. Research was accelerated by genotype 2a (strain JFH1) infectious cell culture systems."

"We previously developed viable JFH1-based recombinants encoding the structural proteins (core, E1, E2), p7, and NS2 of prototype isolates of the seven major HCV genotypes;...

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