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Hepatitis B Virus

Research from Chulalongkorn University Provides New Data on Hepatitis B Virus

Published in Hepatitis Weekly, August 8th, 2011

2011 AUG 8 -- New research, "Cross-species transmission of gibbon and orangutan hepatitis B virus to uPA/SCID mice with human hepatocytes," is the subject of a report. "To investigate the potential of cross-species transmission of non-human primate HBV to humans, severe combined immunodeficiency mice transgenic for urokinase-type plasminogen activator, in which the mouse liver has been engrafted with human hepatocytes, were inoculated with non-human primate HBV. HBV-DNA positive serum samples from a gibbon or orangutan were inoculated into 6 chimeric mice," scientists in Bangkok, Thailand report.

"HBV-DNA, hepatitis B surface antigen (HBsAg), and HB...

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