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Hepatitis C Virus

Researchers at National Institute of Infectious Disease Have Published New Data on Hepatitis C Virus

Published in Hepatitis Weekly, October 10th, 2011

2011 OCT 10 -- Current study results from the report, "Development of recombinant hepatitis C virus with NS5A from strains of genotypes 1 and 2," have been published. "Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) plays multiple and diverse roles in the viral lifecycle, and is currently recognized as a novel target for anti-viral therapy. To establish an HCV cell culture system with NS5A of various strains, recombinant viruses were generated by replacing NS5A of strain JFH-1 with those of strains of genotypes 1 (H77; 1a and Con1; 1b) and 2 (J6CF; 2a and MA; 2b)," scientists in Tokyo, Japan report.

"All these recombinant viruses were capable of...

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