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Ribonucleoproteins

Findings in Ribonucleoproteins Reported from National Cancer Institute

Published in Hepatitis Weekly, October 17th, 2011

2011 OCT 17 -- A new study, "Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line," is now available. According to the authors of recent research from Bethesda, Maryland, "Hepatocellular carcinoma (HCC) is a common cancer, and hepatitis B virus (HBV) is a major etiological agent. Convincing epidemiological and experimental evidence also links HCC to aflatoxin, a naturally occurring mycotoxin that produces a signature p53-249(ser) mutation."

"Recently, we have reported that tumor-derived HBx variants...

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