Published in Hepatitis Weekly, January 9th, 2012
"Hence inhibition of virus at entry step is an important target to identify antiviral drugs against HCV. Methods and result: The present study elaborated the role of CD81 and HCV glycoprotein E2 in HCV entry using retroviral pseudo-particles of 3a local genotype. Our results demonstrated that HCV specific antibody E2 and host antibody CD81 showed dose-dependent inhibition of HCV entry. HCV...
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