Hepatitis B Virus
Investigators at College of Medicine Release New Data on Hepatitis B Virus
Published in Hepatitis Weekly, January 23rd, 2012
2012 JAN 23 -- Investigators publish new data in the report "Impact of hepatitis B virus (HBV) x gene mutations on hepatocellular carcinoma development in chronic HBV infection." According to the authors of a study from Seoul, South Korea, "The hepatitis B virus (HBV) PreS mutations C1653T, T1753V, and A1762T/G1764A were reported as a strong risk factor of hepatocellular carcinoma (HCC) in a meta-analysis. HBV core promoter overlaps partially with HBx coding sequence, so the nucleotide 1762 and 1764 mutations induce HBV X protein (HBx) 130 and 131 substitutions."
"We sought to elucidate the impact of HBx mutations on HCC development. Chronically...
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Source: Hepatitis Weekly (2012-01-23)
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