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Hepatitis B Virus

Investigators from Utah State University Target Hepatitis B Virus

Published in Hepatitis Weekly, March 12th, 2012

2012 MAR 12 -- According to the authors of recent research published in the journal Clinical and Vaccine Immunology, "A hepatitis B virus (HBV) vaccine has been developed using a new adjuvant and HBV surface antigens produced from a CHO cell line. The purified HBV surface antigens are composed of L protein, Mprotein, and S protein in a mixture of 20- and 40-nm-diameter particles and filamentous forms."

"This HBV surface antigen, formulated with L-pampo, a proprietary adjuvant, induced 10 times more antibody than the same antigen with alum and was capable of inducing strong immune responses in three different HBV transgenic mice. In spite of the...

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