Hepatitis B Virus
Recent Findings in Hepatitis B Virus Described by Researchers from University Hospital
Published in Hepatitis Weekly, April 23rd, 2012
2012 APR 23 -- A report, "Hepatitis B virus variant with the a194t substitution within reverse transcriptase before and under adefovir and tenofovir therapy," is newly published data in Clinics and Research In Hepatology and Gastroenterology. "Retrospective analysis of our local HBV reverse transcriptase (rt) sequence database including 973 sequences recovered from 616 patients identified one unique HBV DNA sequence harbouring amino acid (aa) substitution rtA194T, which has been suspected to confer reduced susceptibility to tenofovir but whose implication in antiviral resistance has not been confirmed. This sequence has been recovered from the blood sample of a...
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Source: Hepatitis Weekly (2012-04-23)
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