Laikon General Hospital, Athens

HLA antigens predict disease progression in HIV-infected hemophilia patients

Published in Hospital Business Week, September 25th, 2005

HLA antigens predict disease progression in HIV-infected hemophilia patients.

"Our objective was to assess the influence of genetic factors such as HLA classes I and II antigens and other clinical and laboratory variables on the progression of HIV disease in a cohort of 118 HIV infected hemophilic subjects of Greek origin who had been typed for HLA antigens and were followed up prospectively for 22 years since seroconversion.

"At the end of the follow up we compared two groups of patients: 22 patients who had a fast progression to AIDS (median 6 years since seroconversion) vs. 33 patients who remained asymptomatic in stage A2 for up to 22 years...

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Source: Hospital Business Week (2005-09-25)

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