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Lutfi Kirdar Kartal Research Hospital, Istanbul

Estradiol valerate and dionegest therapy did not increase serum homocysteine levels

Published in Hospital Business Week, January 8th, 2006

Six months of estradiol valerate and dionegest therapy did not increase serum homocysteine levels in postmenopausal women.

According to a study from Turkey, "Several studies have verified that hormone replacement therapy (HRT) has protective effects on postmenopausal women's cardiovascular condition. However, highly significant recent studies have reported that women treated with HRT have more cardiovascular events than untreated women."

"An elevated homocysteine level is one important risk factor for cardiovascular disease (CVD)," asserted Z.M. Pirimoglu and colleagues. "As a good indicator of CVD risk, we examined the changes in plasma homocysteine...

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