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Glioma

Research from Japan, the United States and Germany provides new data about glioma

Published in Hospital Business Week, April 29th, 2007

Studies from Japan, the United States and Germany yield new information about glioma.

Study 1: Investigators publish new data in the report "Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells. The immediate early response gene IEX-1 is involved in the regulation of apoptosis and cell growth. In order to increase the apoptotic sensitivity to chemotherapeutic drugs and gamma-ray, we attempted to establish U87-MG human glioma cell line expressing IEX-1," scientists in Gifu, Japan report.

"Unexpectedly, however, transfection of IEX-1 into U87-MG glioma cells resulted in morphological changes to astrocytic phenotype...

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