Pathology
New findings reported from Kyung-Hee University, Department of Pathology describe advances in pathology
Published in Hospital Business Week, April 29th, 2007
Current study results from the report, "Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarcomas," have been published. "Ewing sarcoma is a highly malignant tumor of bone preferentially arising in children and young adults. Its 5-year survival rate is only 50% despite the use of multimodal therapeutic approaches, requiring a search for new therapeutic targets and the development of novel therapeutic modalities," researchers in Seoul, Korea report.
"KIT and PDGFRs are type III receptor tyrosine kinases, and activating mutations in c-kit (which encodes KIT) and PDGFRs have been reported as oncogenic events in many malignancies. Imatinib is a...
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