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Hyperoxia

Recent findings from Chang-Gung University highlight research in hyperoxia

Published in Hospital Business Week, May 6th, 2007

Fresh data on hyperoxia are presented in the report "Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment. Large-tidal volume (VT) mechanical ventilation and hyperoxia used in patients with acute respiratory distress syndrome can damage pulmonary epithelial cells through lung inflammation and apoptotic cell death. Hyperoxia has been shown to increase ventilator-induced lung injury, but the mechanisms regulating interaction between large VT and hyperoxia are unclear," scientists in Taoyuan, Taiwan report.

"We hypothesized that the addition of hyperoxia to large-VT ventilation would increase...

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