Carcinoma Genetics
New carcinoma genetics research from University Hospital outlined
Published in Hospital Business Week, August 5th, 2007
Data detailed in "Association of the BRCA1 missense variant R1699W with a malignant phyllodes tumor of the breast" have been presented. "Familial breast carcinomas that are attributable to BRCA1 or BRCA2 mutations have characteristic morphologic and immunhistochemical features. BRCA1-associated carcinomas are poorly differentiated infiltrating ductal carcinomas frequently exhibiting morphologic features of typical or atypical medullary carcinomas such as prominent lymphocytic infiltrate and pushing margins," scientists writing in the journal Cancer Genetics and Cytogenetics report.
"We report on a patient carrying the deleterious BRCA1 germline mutation R1699W,...
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