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Myeloma

Findings from Odense University broaden understanding of myeloma

Published in Hospital Business Week, August 5th, 2007

"Interphase fluorescence in-situ hybridization (i-FISH) was used to investigate 192 patients with multiple myeloma (MM; n = 182) and benign monoclonal gammopathy of undetermined significance (MGUS; n = 10). Of the 182 MM cases, 132 were investigated without and 50 with positive plasma cell identification (PC-ID+); 134 were investigated at diagnosis, 32 at time of progression, 7 at time of relapse, and 9 were investigated with partial remission or no response," scientists in Odense, Denmark report.

"The FISH analysis detected 11q23 (n = 61), 13q13 similar to q14 (n = 181), 14q32 (n = 121), 17p13.1 (n = 18 1), t(4; 14) (n = 76), and t(t 1;14) (n = 73). Of the 132 patients...

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