Life Sciences
New life sciences study results reported from University Hospital
Published in Hospital Business Week, September 9th, 2007
A report, "MxA-independent inhibition of Hantaan virus replication induced by type I and type II interferon in vitro," is newly published data in Virus Research. "Interferons (IFN) induce an antiviral state against Hantaan virus (HTNV) but the mechanisms responsible for inhibition are unclear. The IFN-inducible MxA is discussed to be important for control of infections with hantaviruses," investigators in Berlin, Germany report.
"To characterize the role of endogenous MxA, the inhibition of HTNV induced by type I and type II IFNs was compared in Vero and A549 cells. IFNalpha and IFNgamma reduced production of infectious virions, viral RNA, and nucleocapsid...
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