Mumps
Research in the area of mumps reported from N. Rosas-Murrieta and colleagues
Published in Hospital Business Week, September 16th, 2007
Research findings, "Differential sensitivity to interferon influences the replication and transcription of Urabe AM9 mumps virus variants in nerve cells," are discussed in a new report. "Urabe AM9 mumps virus vaccine causes post-vaccination meningitis. Two variants of Urabe AM9 virus differ in their replication efficiency in human nerve cells, HN-A(1081) variant being more neurotropic than HN-G(1081)," investigators in Metepec, Mexico report.
"The effect of interferon (IFN) on viral replication and transcription was analyzed. Priming of nerve cells with IFN reduced more significantly the replication of HN-G(1081) variant (from 10(2.5) to 10(1.3) TCID(50)) than that of...
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