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Synovitis

Research on synovitis reported by scientists at Royal Free Hospital, Department of Orthopaedics

Published in Hospital Business Week, November 4th, 2007

Scientists discuss in 'Diagnosis of haemophilic synovitis' new findings in synovitis. According to recent research from London, the United Kingdom, "'The pathophysiology of haemophilic synovitis is complex and not as well understood on a molecular level as we have thought. The repeated bleeding episodes and synovial hypertrophy occurring within the joint."

"Iron and other red-cell debris are phagocytized, and hydrolytic enzymes are produced leading to the destruction of articular cartilage is a simplistic model. However, how iron stimulates this destructive cascade remains speculative and poorly understood," wrote N.J. Goddard and colleagues, Royal Free Hospital,...

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