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Cancer Oncology

Researchers from Royal Marsden Hospital, Department of Medicine detail findings in cancer oncology

Published in Hospital Business Week, November 4th, 2007

Researchers detail in 'Potential clinical applications of epothilones: a review of phase II studies,' new data in cancer. According to recent research published in the journal Annals of Oncology, "' Epothilones are cytotoxic macrolides that share a similar mechanism of action with the taxanes but demonstrate antitumor activity in taxane-resistant settings. Six epothilones are in early clinical trials for cancer treatment."

"This review summarizes data from phase II clinical studies of the epothilones ixabepilone (BMS-247550), patupilone (EPO906), and KOS-862. Data were identified by searches of PubMed and of the proceedings of the American Society of Clinical...

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