Human Papillomavirus

Researchers' work from Chinese University of Hong Kong focuses on human papillomavirus

Published in Hospital Business Week, December 2nd, 2007

"The clinical utility of viral-load and integration status of human papillomavirus (HPV) infection remains uncertain. We examined 75 women infected with HPV58, a worldwide rare type found to be prevalent in cervical cancers in eastern Asia," investigators in Hong Kong, People's Republic of China report.

"Viral load was significantly higher for cervical intraepithelial neoplasia (CIN) 1/2, but those for a normal control group and for CIN 3 or cancer overlapped substantially. A pure integrated genome was found for all lesion grades, giving a poor positive predictive value (23.1%) for cancer. The pure episomal form's negative predictive value for cancer was only 76.3%....

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Source: Hospital Business Week (2007-12-02)

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