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Heart Disease

Research from T. Sadanaga and co-authors reveals new findings on heart disease

Published in Hospital Business Week, December 9th, 2007

"The aim of the present study is to elucidate the effect of bepridil on heart rate-dependent QT prolongation in patients with or without structural heart disease," investigators in Yatsushiro, Japan report.

"QT intervals and the preceding R-R intervals were randomly measured by 24-hour Holter electrocardiogram in 29 patients with symptomatic arrhythmias. The slope of the regression curve was used as a marker of bradycardia-dependent QT prolongation. The slope was not different in patients without structural heart disease (0.34 +/- 0.10) as compared with the apparently normal control subjects (0.32 +/- 0.057, n = 29), whereas it was larger than that in patients with...

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