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Cord Blood

Study data from C. Pratvidal and colleagues update understanding of cord blood

Published in Hospital Business Week, December 16th, 2007

According to recent research from Barcelona, Spain, "Umbilical cord blood (UCB) has been widely used for hematopoietic stem cell transplantation. The UCB-derived stem cells (UCBSCs) have been proposed as an alternative to bone marrow (BM)-derived mesenchymal stem cells (MSCs) for cardiac cell-based therapy."

"Herein we studied whether UCBSCs spontaneously exhibit cardiac-specific markers in vitro. Human UCBSCs were isolated, expanded, and phenotyped by flow cytometry, quantitative RT-PCR, and immunofluorescence. Cell pluripotency and proliferation were also assessed by adipogenic and osteogenic media and in growth assays. Among 25 analyzed UCB, 16% of cases afforded...

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