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Aortic Aneurysms

Reports from M.J. Collins and colleagues advance knowledge in aortic aneurysms

Published in Hospital Business Week, May 25th, 2008

"Ascending aortic aneurysms ( AA) are a common, though poorly understood medical condition. To document the histological changes in a large series of human ascending AA, and to correlate these changes with clinical variables," investigators in Toronto, Canada report.

"111 ascending AA were excised at surgery over a 3 year period. Each aneurysm was received as a continuous ring of tissue. Sections were taken from the anterior, posterior, greater and lesser curvature of the aorta and graded in a semi-quantitative fashion for the degree of elastin fragmentation, elastin loss, smooth muscle cell (SMC) loss, intimal changes and inflammation. Mean patient age at surgery was...

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