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Reports from S. Rheims and co-researchers add new data to research in health and medicine

Published in Hospital Business Week, October 12th, 2008

According to a study from Lyon, France, " Despite guidelines establishing the need to perform comprehensive paediatric drug development programs, pivotal trials in children with epilepsy have been completed mostly in Phase IV as a postapproval replication of adult data. However, it has been shown that the treatment response in children can differ from that in adults."

"It has not been investigated whether differences in drug effect between adults and children might occur in the treatment of drug-resistant partial epilepsy, although such differences may have a substantial impact on the design and results of paediatric randomised controlled trials (RCTs). Methods and...

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