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Neuroblastoma Therapy

Researchers' work from G. Gaslini Children's Hospital focuses on neuroblastoma therapy

Published in Hospital Business Week, December 14th, 2008

Data detailed in 'Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin' have been presented. According to recent research from Genoa, Italy, "In vivo evaluation of good manufacturing practice-grade targeted liposomal doxorubicin (TVT-DOX), bound to a CD13 isoform expressed on the vasculature of solid tumors, in human tumor xenografts of neuroblastoma, ovarian cancer, and lung cancer. Mice were implanted with lung, ovarian, or neuroblastoma tumor cells via the pulmonary, peritoneal, or orthotopic (adrenal gland) routes, respectively, and treated, at different days post inoculation, with multiple doses of doxorubicin, administered either free or...

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