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Cardiac Surgery

Studies in the area of cardiac surgery reported from A. Zangrillo and co-researchers

Published in Hospital Business Week, March 22nd, 2009

"Perioperative microvascular bleeding is associated with increased morbidity and mortality and could be reduced by hemostatic drugs such as recombinant activated factor VII (rFVIIa). Few trials have investigated rFVIIa and each individually lacked power to detect a beneficial effect on transfusion of blood products or thromboembolic side effects. Meta-analysis. Hospitals," scientists in Milan, Italy report.

"The authors performed a meta-analysis of 5 clinical trials (1 randomized, 3 propensity matched, and 1 case matched) that included 298 patients and indicated major clinical outcome (survival and thromboembolic events). Four of the 5 studies used rFVII in refractory...

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