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Angiogenesis

New research on angiogenesis from Y.L. Kim and co-authors summarized

Published in Hospital Business Week, April 26th, 2009

According to recent research from South Korea, "Ultrafiltration failure (UFF) continues to be a major complication of peritoneal dialysis (PD), particularly long-term PD. Continuous exposure to bioincompatible PD solutions causes inflammation of the peritoneal membrane, which progressively undergoes fibrosis and angiogenesis and, ultimately, UFF."

"There is emerging evidence that epithelial mesenchymal transition (EMT) of peritoneal mesothelial cells (MCs) may play an important role in the failure of peritoneal membrane function. Submesothelial myofibroblasts originating from MCs through EMT and from activated resident fibroblasts participate in inflammatory responses,...

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