Breast Cancer
Researchers at St. Mary's Hospital have published new data on breast cancer
Published in Hospital Business Week, August 16th, 2009
"In up to 75% of breast cancers, estrogen receptor (ER) signaling is a key promoter of tumor proliferation, and inhibition of this pathway has clear therapeutic efficacy. The principal clinical means of inhibiting ER signaling comprise selective ER modulators, such as tamoxifen, that act as partial receptor agonists; measures to reduce the circulating level of estrogen, including ovarian ablation, gonadotropin-releasing hormone analogues, and aromatase inhibition; and antagonism and downregulation of ER by the antiestrogen fulvestrant," scientists in London, the United Kingdom report.
"Each of these therapies is effective in a proportion of ER-positive breast cancers,...
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