4SC AG
4SC Commences Phase II Trial in Hepatocellular Carcinoma HCC with the HDAC Inhibitor 4SC-201
Published in Hospital Business Week, September 6th, 2009
4SC AG (Frankfurt, Prime Standard: VSC) the German drug discovery and development company, announced the dosing of the first patient in its Phase II trial with 4SC-201 (resminostat), a pan-histone deacetylase (HDAC) inhibitor, as a new potential treatment option for patients with advanced hepatocellular carcinoma (HCC), the most frequent form of liver cancer. This proof-of-concept (POC) study will evaluate 4SC-201 as a second line therapy in this indication, for which only a single first line therapy drug is currently approved.
The 'Shelter' study, entitled 'A proof-of-concept Phase II study to evaluate efficacy, safety and pharmacokinetics of 4SC-201 and of the...
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