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Vasculitis

New vasculitis study findings have been published by scientists at Peking University

Published in Hospital Business Week, January 3rd, 2010

"Patients with pauci-immune crescentic glomerulonephritis (CrGN) are frequently found to have antineutrophil cytoplasmic antibodies (ANCAs). It has been demonstrated that ANCAs can induce neutrophil activation and degranulation, which plays an important role in the pathogenesis of ANCA-associated vasculitis," investigators in Beijing, People's Republic of China report.

"However, the pathogenesis of ANCA-negative pauci-immune CrGN is not clear. This study aims to investigate the evidence for neutrophil activation and degranulation at disease presentation in patients with renal biopsy-proven ANCA-negative pauci-immune CrGN. Sera from 20 patients with ANCA-negative...

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