St. Vincents University Hospital
Ets-1 transcription factors are involved in human breast cancer metastasis
Published in Hospital Law Weekly, December 9th, 2004
"The Ets family of transcription factors regulate expression of multiple genes involved in tumor progression. The aim of this study was to investigate the expression of Ets-1 in a large panel of human breast cancers and relate its levels to the parameters of tumor progression and metastasis. Using reverse transcription-polymerase chain reaction (RT-PCR), Ets-1 mRNA was detected in 30 out of 42 (71%) fibroadenomas and 131 out of 179 (73%) primary breast carcinomas," scientists in Ireland report.
"Similarly, levels of Ets-1 mRNA were not significantly different in fibroadenomas...
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Source: Hospital Law Weekly (2004-12-09)
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