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Bioerevna Medical Center, Athens

Association among factor V, prothrombin mutations, and oral cancer risk studied

Published in Hospital Law Weekly, September 29th, 2005

Researchers investigated the association among factor V, prothrombin mutations, and the heightened risk of thrombosis and oral cancer.

"Methylenetetrahydrofolate reductase is associated with pathogenesis of both thrombosis and oral cancer. Therefore, a search for a similar association of other thrombosis-related factors with oral cancer is justified. In order to investigate whether the coagulation factor V Leiden and prothrombin G20210A mutations increase the risk of oral cancer, we searched for these mutant alleles by RFLP analysis in DNA samples of 102 patients with oral cancer and 120 healthy controls," scientists writing in the journal Anticancer Research...

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