Published in Hospital Law Weekly, September 29th, 2005
According to recent research published in the journal Human Immunology, "KIR and HLA loci are both highly polymorphic, and some HLA class 1 products bind and trigger cell-surface receptors specified by KIR genes. We examined whether KIR genes act in concert with HLA-B locus to control HIV-1 infection in a sample of Zambian patients.
"DNA samples from 88 Zambian patients with HIV-1 were examined. Patients were classified as either slow progressors (SP; n=54) or rapid progressors (RP; n=34) to AIDS. All were typed for HLA-B and KIR genes."
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