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Italian Hospital of Buenos Aires, Buenos Aires, Argentina

Neointimal proliferation is inhibited by irinotecan-eluting stents in rabbit aortas

Published in Hospital Law Weekly, September 7th, 2006

Neointimal proliferation is inhibited by irinotecan-eluting stents in hypercholesterolemic rabbit aortas.

Researchers in Argentina conducted a study "to assess the effect of irinotecan-eluting stents (IS) on neointimal growth in the aortas of hypercholesterolemic rabbits and to determine other local histopathological effects such as necrosis, fibrin, and inflammatory reaction."

"Phosphorylcholine-coated stents were deployed in the aortas of hypercholesterolemic rabbits, wrote wrote D.H. Berrocal and colleagues at the Italian Hospital of Buenos Aires. "Group 1 (control; n=8) received unloaded stents, group 2 (n=7) and group 3 (n=9) received IS with...

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