Acute Myeloid Leukemia

Reports outline acute myeloid leukemia in children study findings from Children's Hospital, Department of Women's and Children's Health

Published in Hospital Law Weekly, November 30th, 2006

Research findings, "Etoposide pharmacokinetics in children treated for acute myeloid leukemia," are discussed in a new report. "We studied the pharmacokinetics of etoposide in 45 children treated for newly diagnosed acute myeloid leukemia. Etoposide, 100 mg/m body surface area/24 h, was administered by 96-h continuous intravenous infusion," scientists in Uppsala, Sweden report.

"Concomitantly, the children received cytarabine 200 mg/m/24 h by intravenous infusion and 6-thioguanine 100 mg/m twice daily orally. Median total body clearance in children 0.5-1.8 (n=4) and 2.3-17.7 years old (n=36) without Down's syndrome was 17.1 and 17.6 ml/min/m, respectively (p=0.96). Five...

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Source: Hospital Law Weekly (2006-11-30)

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