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Monoclonal Antibodies

Data on monoclonal antibodies published by researchers at Queen Mary Hospital

Published in Hospital Law Weekly, March 1st, 2007

New investigation results, "Regular virologic surveillance showed very frequent cytomegalovirus reactivation in patients treated with alemtuzumab," are detailed in a study published in American Journal of Hematology. According to recent research from Hong Kong, "Ten patients with refractory lymphomas or autoimmune cytopenias were treated with alemtuzumab, and monitored prospectively for cytomegalovirus (CMV) reactivation by antigenemia and polymerase chain reaction. All patients showed virologic CMV reactivation."

"Two patients developed pneumonitis and hepatitis respectively, necessitating alemtuzumab withdrawal. Eight patients were asymptomatic, and with pre-emptive...

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