Hemolytic Uremic Syndrome
Researchers from Malmo University, Department of Laboratory Medicine report recent findings in hemolytic uremic syndrome
Published in Hospital Law Weekly, March 29th, 2007
Investigators publish new data in the report "A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation." According to a study from Malmo, Sweden, "Factor I (FI) is the major complement inhibitor that degrades C3b and C4b in the presence of cofactors such as factor H (FH) and membrane cofactor protein (MCP). Recently, mutations and polymorphisms in complement regulator molecules FH and MCP but also in FI have been associated with atypical hemolytic uremic syndrome (aHUS)."
"HUS is a disorder characterized by hemolytic anemia, thrombocytopenia and acute renal failure. In this study,...
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Source: Hospital Law Weekly (2007-03-29)
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