Anesthesia

Study results from Muenster University broaden understanding of anesthesia

Published in Hospital Law Weekly, September 6th, 2007

"Ropivacaine is primarily a local anesthetic, but it also acts as a vasoactive agent. Case reports have described a critical reduction in blood flow when higher concentrations of ropivacaine were used for peripheral-nerve blocks," scientists writing in the journal Regional Anesthesia and Pain Medicine report.

"One hypothesis is that local application of ropivacaine in tissues supplied by end arteries reduces tissue blood flow because of arterial vasoconstriction. Rats were anesthetized by inhalation of isoflurane. The tail vessels were carefully dissected from the ventral side near the radix. Randomly, normal saline, prilocaine 0.5%, prilocaine 0.5% with...

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Source: Hospital Law Weekly (2007-09-06)

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