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Glioma Genetics

Findings from Sahlgrenska University, Institute of Biomedicine provide new insights into glioma genetics

Published in Hospital Law Weekly, January 3rd, 2008

New investigation results, 'Oncostatin M-induced genes in human astrocytomas,' are detailed in a study published in International Journal of Oncology. According to recent research published in the International Journal of Oncology, "Oncostatin M (OSM) is a member of the interleukin-6 (IL-6) cytokine family and known to be induced in the nervous system as a result of cell stress. OSM is expressed in most human brain tumors, but the effects on tumor cells are unclear."

"The cytokine is known to activate the JAK/STAT signaling pathway by binding to its receptors gp130/OSMbeta or gp130/LIFRbeta and thereby initiating activation or suppression of a number of...

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