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Hydrocephalus

Research on hydrocephalus detailed by R. Bayston and co-authors

Published in Hospital Law Weekly, January 31st, 2008

According to recent research from Nottingham, the United Kingdom, "Propionibacterium acnes is increasingly recognized as a cause of delayed infection after spinal instrumentation or shunting for hydrocephalus. Biofilm development by this organism has recently been demonstrated."

"We therefore investigated the effect of two different courses of three antibiotics (penicillin, rifampicin and linezolid) on mature P. acnes biofilms in vitro. Outcomes were eradication or regrowth after withdrawal of antibiotics, simulating successful treatment and relapse. P. acnes biofilms were grown on titanium discs for 6 days until mature, then exposed to the antibiotics for either 7 or...

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