Life Sciences

Data on life sciences published by researchers at Brigham and Women's Hospital

Published in Hospital Law Weekly, July 24th, 2008

Fresh data on life sciences are presented in the report 'Role of Ets-1 phosphorylation in the effector function of Th cells.' According to a study from the United States, "The transcription factor Ets-1 critically regulates differentiation and function of T helper (Th) cells. In vitro studies have demonstrated that DNA binding and transcriptional activity of Ets-1 are regulated by phosphorylation."

"Depending on the site of phosphorylation, Ets-1 function can either be increased or inhibited. In addition, a splice variant lacking several inhibitory phosphorylation sites has been identified, raising the possibility that this splice variant may function differently from...

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Source: Hospital Law Weekly (2008-07-24)

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