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Research from T. Lucas and co-authors provides new data about life sciences

Published in Hospital Law Weekly, August 14th, 2008

"It is becoming increasingly clear that interactions between cancer cells, stroma cells and the extracellular matrix (ECM) are pivotal to the processes of neovascularization and tumorigenesis. As tumor stromal components known as tumor associated macrophages (TAMs), mononuclear phagocytes can play a key role in tumor type specific neoangiogenesis by promoting remodeling of the ECM through the production of matrix metalloproteases (MMPs), secreting pro-angiogenic growth factors and stabilizing the tumor vasculature," investigators in Vienna, Austria report.

"The growth factor colony-stimulating factor-1 is produced by a wide variety of cancer cells and tumor stroma cells...

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