Chronic Obstructive Pulmonary Disease

Researchers at Copenhagen University have published new data on chronic obstructive pulmonary disease

Published in Hospital Law Weekly, December 18th, 2008

According to recent research published in the American Journal of Respiratory and Critical Care Medicine, "Superoxide dismutase (SOD) 3 inhibits oxidative fragmentation of lung matrix components Collagen 1, hyaluronan, and heparan sulfate. Inherited change in SOD3 expression or function could affect lung matrix homeostasis and influence pulmonary function."

"To identify novel SOD3 polymorphisms that are associated with lung function or chronic obstructive pulmonary disease (COPD). Resequencing of 182 individuals identified two novel polymorphisms, E1 (rs8192287) and I1 (rs8192288), in a conserved region of the SOD3 gene of potential relationship to lung function....

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Source: Hospital Law Weekly (2008-12-18)

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