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Human Papillomavirus

Investigators at Brigham and Women's Hospital have published new data on human papillomavirus

Published in Hospital Law Weekly, January 1st, 2009

"Dynein is a minus end-directed microtubule motor that transports numerous cargoes throughout the cell. During mitosis, dyncin motor activity is necessary for the positioning of spindle microtubules and has also been implicated in inactivating the spindle assembly checkpoint," investigators in the United States report.

"Mutations in dynein motor and/or accessory proteins are associated with human disease, including cancer, and the delocalization of dynein from mitotic spindles has been correlated with an increased incidence of multipolar spindle formation in some cancer cells that contain supernumerary centrosomes. The high-risk human papillomavirus type 16 (HPV16) E7...

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