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Cancer

Reports summarize cancer study results from Royal Melbourne Hospital

Published in Hospital Law Weekly, June 25th, 2009

According to recent research from Parkville, Australia, "Although experiments in rodents and human population-based studies have demonstrated the efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) such as sulindac in colorectal cancer (CRC) prevention, a detailed knowledge of the underlying mechanism of action of this drug is limited. To better understand the chemopreventitive effects of sulindac, especially early sulindac-induced apoptotic events, we used the CRC cell line LIM1215 as an experimental model, focusing on proteins secreted into the LIM1215 culture medium - i.e., the secretome."

"This subproteome comprises both soluble-secreted proteins and exosomes...

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