Published in Hospital Law Weekly, October 15th, 2009
"In this study we investigated the causal links between glutathione, NF-kappa B and hepatocyte damage. HepG2 and 3B cells were exposed to different doses of H2O2 or N-acetyl-cysteine (NAC) and the proliferation/apoptosis rate, glutathione forms, and p65NF-kappa B glutathionylation and activity were analysed. Our results demonstrate that H2O2 stopped proliferative response at low doses, but induced apoptosis only at high...
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