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Cancer Gene Therapy

Study results from L.P. Song et al provide new insights into cancer gene therapy

Published in Hospital Law Weekly, February 4th, 2010

In this recent report published in the World Journal of Gastroenterology, researchers in Xian, People's Republic of China conducted a study "To construct the recombinant lentivirus expression plasmid, pLenti6/V5-NT4p53(N15)-antennapedia (Ant), and study its effect on HepG2 cells. Plasmid pLenti6/V5-NT4p53(N15)-Ant was constructed incorporating the following functional regions, including signal peptide sequence and pro-region of neurotrophin 4, N-terminal residues 12-26 of p53 and 17 amino acid drosophila carrier protein, Ant."

"Hepatocellular carcinoma (HepG2) cells were used for transfection. 3-[4,5-dimethyl-thiazol-2yl]-2,5 diphenyl tetrazolium bromide (MTT)...

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