Apoptosis Therapy
Scientists at Children's Hospital of Philadelphia, Division of Oncology discuss research in apoptosis therapy
Published in Hospital Law Weekly, March 4th, 2010
New investigation results, 'Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists,' are detailed in a study published in Cancer Biology & Therapy. According to a study from the United States, "Neuroblastoma (NB) is a common, highly lethal pediatric cancer, with treatment failures largely attributable to the emergence of chemoresistance. The pro-survival Bcl2 homology (BH) proteins critically regulate apoptosis, and may represent important therapeutic targets for restoring drug sensitivity in NB."
"We used a human NB tumor tissue microarray to survey the expression of pro-survival BH proteins Mcl1 and...
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Source: Hospital Law Weekly (2010-03-04)
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